2025-2031 Global Estrogen API Industry Research & Trends Analysis Report- YH Research

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2025-2031 Global Estrogen API Industry Research & Trends Analysis Report

Publication Date: 2025-12-09
Report Id: 2466391
Industry: Pharma & Healthcare
Report Page: 122
Chart: 129

PDF Download

Publication Date: 2025-12-09
Report Id: 2466391
Industry: Pharma & Healthcare
Report Page: 122
Chart: 129

PDF Download

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Table of Contents
Description
Table of Figures
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1 Market Overview
1.1 Estrogen API Definition
1.2 Global Estrogen API Market Size and Forecast
1.2.1 By Revenue, Global Estrogen API Market Size, 2020-2031
1.2.2 By Sales Volume, Global Estrogen API Market Size, 2020-2031
1.2.3 Global Estrogen API Price Trend, 2020-2031
1.3 China Estrogen API Market Size and Forecast
1.3.1 By Revenue, China Estrogen API Market Size, 2020-2031
1.3.2 By Sales Volume, China Estrogen API Market Size, 2020-2031
1.3.3 China Estrogen API Price Trend, 2020-2031
1.4 China Percentage in Global Market
1.4.1 By Revenue, China Estrogen API Share in Global Market, 2020-2031
1.4.2 By Sales Volume, China Estrogen API Share in Global Market, 2020-2031
1.4.3 Estrogen API Market Size: China VS Global, 2020-2031
1.5 Estrogen API Market Dynamics
1.5.1 Estrogen API Market Drivers
1.5.2 Estrogen API Market Restraints
1.5.3 Estrogen API Industry Trends
1.5.4 Estrogen API Industry Policy

2 Global Competitive Landscape by Company
2.1 Global Estrogen API Revenue by Company, 2020-2025
2.2 Global Estrogen API Sales Volume by Company, 2020-2025
2.3 Global Estrogen API Price by Company, 2020-2025
2.4 Global Estrogen API Participants, Market Position (Tier 1, Tier 2, and Tier 3)
2.5 Global Estrogen API Concentration Ratio
2.6 Global Estrogen API Mergers & Acquisitions, Expansion Plans
2.7 Global Estrogen API Manufacturers Product Type

3 China Competitive Landscape by Company
3.1 China Estrogen API Revenue by Company, 2020-2025
3.2 China Estrogen API Sales Volume by Company, 2020-2025
3.3 China Estrogen API Estrogen API Participants, Market Position (Tier 1, Tier 2, and Tier 3)
3.4 China Estrogen API Market, Sales Percentage of Local Players VS Foreign Players (2020-2025)
3.5 Chinese Local Players, Estrogen API Domestic VS Export
3.6 China Market, Estrogen API Import & Export
3.6.1 China Market, Estrogen API Import & Export, 2020-2031
3.6.2 China Estrogen API Import & Export Trends
3.6.3 Main Sources of China Estrogen API Import
3.6.4 Export Destination of China Estrogen API

4 Estrogen API Production by Region
4.1 Global Estrogen API Capacity, Production and Capacity Utilization, 2020-2031
4.2 Global Geographic Distribution of Estrogen API Manufacturers
4.3 Global Major Manufacturers, Estrogen API Capacity Expansion and Future Plans
4.4 Global Estrogen API Capacity by Region
4.5 Global Estrogen API Production by Region
4.5.1 Global Estrogen API Production & Forecast by Region, 2020 VS 2024 VS 2031
4.5.2 Global Estrogen API Production by Region, 2020-2025
4.5.3 Global Estrogen API Production Market Share & Forecast by Region, 2020-2031

5 Industry Chain Analysis
5.1 Estrogen API Industry Chain
5.2 Estrogen API Upstream Analysis
5.2.1 Estrogen API Core Raw Materials
5.2.2 Main Manufacturers of Estrogen API Core Raw Materials
5.3 Midstream Analysis
5.4 Downstream Analysis
5.5 Estrogen API Production Mode
5.6 Estrogen API Procurement Model
5.7 Estrogen API Industry Sales Model and Sales Channels
5.7.1 Estrogen API Sales Model
5.7.2 Estrogen API Typical Distributors

6 Sights by Type
6.1 Estrogen API Classification by Type
6.1.1 Estradiol Series
6.1.2 Estriol Series
6.1.3 Estrone Series
6.2 by Type, Global Estrogen API Market Size & CAGR, 2020 VS 2024 VS 2031
6.3 by Type, Global Estrogen API Revenue, 2020-2031
6.4 by Type, Global Estrogen API Sales Volume, 2020-2031
6.5 by Type, Global Estrogen API Price, 2020-2031

7 Sights by Hormone Type
7.1 Estrogen API Classification by Hormone Type
7.1.1 Estradiol
7.1.2 Ethinylestradiol
7.1.3 Estriol
7.1.4 Estrone
7.1.5 Other
7.2 by Hormone Type, Global Estrogen API Market Size & CAGR, 2020 VS 2024 VS 2031
7.3 by Hormone Type, Global Estrogen API Revenue, 2020-2031
7.4 by Hormone Type, Global Estrogen API Sales Volume, 2020-2031
7.5 by Hormone Type, Global Estrogen API Price, 2020-2031

8 Sights by Source
8.1 Estrogen API Classification by Source
8.1.1 Natural Hormones
8.1.2 Synthetic Hormones
8.2 by Source, Global Estrogen API Market Size & CAGR, 2020 VS 2024 VS 2031
8.3 by Source, Global Estrogen API Revenue, 2020-2031
8.4 by Source, Global Estrogen API Sales Volume, 2020-2031
8.5 by Source, Global Estrogen API Price, 2020-2031

9 Sights by Application
9.1 Estrogen API Segment by Application
9.1.1 Oral Preparation
9.1.2 Topical Preparations
9.2 by Application, Global Estrogen API Market Size & CAGR, 2020 VS 2024 VS 2031
9.3 by Application, Global Estrogen API Revenue, 2020-2031
9.4 by Application, Global Estrogen API Sales Volume, 2020-2031
9.5 by Application, Global Estrogen API Price, 2020-2031

10 Sales Sights by Region
10.1 By Region, Global Estrogen API Market Size, 2020 VS 2024 VS 2031
10.2 By Region, Global Estrogen API Revenue, 2020-2031
10.3 By Region, Global Estrogen API Sales Volume, 2020-2031
10.4 North America
10.4.1 North America Estrogen API Market Size & Forecasts, 2020-2031
10.4.2 By Country, North America Estrogen API Market Size Market Share
10.5 Europe
10.5.1 Europe Estrogen API Market Size & Forecasts, 2020-2031
10.5.2 By Country, Europe Estrogen API Market Size Market Share
10.6 Asia Pacific
10.6.1 Asia Pacific Estrogen API Market Size & Forecasts, 2020-2031
10.6.2 By Country/Region, Asia Pacific Estrogen API Market Size Market Share
10.7 South America
10.7.1 South AmericaEstrogen API Market Size & Forecasts, 2020-2031
10.7.2 By Country, South America Estrogen API Market Size Market Share
10.8 Middle East & Africa

11 Sales Sights by Country Level
11.1 By Country, Global Estrogen API Market Size & CAGR，2020 VS 2024 VS 2031
11.2 By Country, Global Estrogen API Revenue, 2020-2031
11.3 By Country, Global Estrogen API Sales Volume, 2020-2031
11.4 United States
11.4.1 United States Estrogen API Market Size, 2020-2031
11.4.2 By Company, United States Estrogen API Sales Volume Market Share, 2024
11.4.3 by Type, United States Estrogen API Market Size, Share, 2024 VS 2031
11.4.4 by Application, United States Estrogen API Market Size, Share, 2024 VS 2031
11.5 Europe
11.5.1 Europe Estrogen API Market Size, 2020-2031
11.5.2 By Company, Europe Estrogen API Sales Volume Market Share, 2024
11.5.3 by Type, Europe Estrogen API Market Size, Share, 2024 VS 2031
11.5.4 by Application, Europe Estrogen API Market Size, Share, 2024 VS 2031
11.6 China
11.6.1 China Estrogen API Market Size, 2020-2031
11.6.2 By Company, China Estrogen API Sales Volume Market Share, 2024
11.6.3 by Type, China Estrogen API Market Size, Share, 2024 VS 2031
11.6.4 by Application, China Estrogen API Market Size, Share, 2024 VS 2031
11.7 Japan
11.7.1 Japan Estrogen API Market Size, 2020-2031
11.7.2 By Company, Japan Estrogen API Market Share, 2024
11.7.3 by Type, Japan Estrogen API Market Size, Share, 2024 VS 2031
11.7.4 by Application, Japan Estrogen API Market Size, Share, 2024 VS 2031
11.8 South Korea
11.8.1 South Korea Estrogen API Market Size, 2020-2031
11.8.2 By Company, South Korea Estrogen API Market Share, 2024
11.8.3 by Type, South Korea Estrogen API Market Size, Share, 2024 VS 2031
11.8.4 by Application, South Korea Estrogen API Market Size, Share, 2024 VS 2031
11.9 Southeast Asia
11.9.1 Southeast Asia Estrogen API Market Size, 2020-2031
11.9.2 By Company, Southeast Asia Estrogen API Market Share, 2024
11.9.3 by Type, Southeast Asia Estrogen API Market Size, Share, 2024 VS 2031
11.9.4 by Application, Southeast Asia Estrogen API Market Size, Share, 2024 VS 2031
11.10 India
11.10.1 India Estrogen API Market Size, 2020-2031
11.10.2 By Company, India Estrogen API Market Share, 2024
11.10.3 by Type, India Estrogen API Market Size, Share, 2024 VS 2031
11.10.4 by Application, India Estrogen API Market Size, Share, 2024 VS 2031
11.11 Middle East & Africa
11.11.1 Middle East & Africa Estrogen API Market Size, 2020-2031
11.11.2 By Company, Middle East & Africa Estrogen API Market Share, 2024
11.11.3 by Type, Middle East & Africa Estrogen API Market Size, Share, 2024 VS 2031
11.11.4 by Application, Middle East & Africa Estrogen API Market Size, Share, 2024 VS 2031

12 Manufacturers Profile
12.1 EUROAPI
12.1.1 EUROAPI Company Information, Head Office, Market Area, and Industry Position
12.1.2 EUROAPI Estrogen API Models, Specifications, and Application
12.1.3 EUROAPI Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.1.4 EUROAPI Company Profile and Main Business
12.1.5 EUROAPI Recent Developments
12.2 Symbiotec
12.2.1 Symbiotec Company Information, Head Office, Market Area, and Industry Position
12.2.2 Symbiotec Estrogen API Models, Specifications, and Application
12.2.3 Symbiotec Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.2.4 Symbiotec Company Profile and Main Business
12.2.5 Symbiotec Recent Developments
12.3 Valdepharm (Fareva)
12.3.1 Valdepharm (Fareva) Company Information, Head Office, Market Area, and Industry Position
12.3.2 Valdepharm (Fareva) Estrogen API Models, Specifications, and Application
12.3.3 Valdepharm (Fareva) Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.3.4 Valdepharm (Fareva) Company Profile and Main Business
12.3.5 Valdepharm (Fareva) Recent Developments
12.4 Gonane Pharma
12.4.1 Gonane Pharma Company Information, Head Office, Market Area, and Industry Position
12.4.2 Gonane Pharma Estrogen API Models, Specifications, and Application
12.4.3 Gonane Pharma Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.4.4 Gonane Pharma Company Profile and Main Business
12.4.5 Gonane Pharma Recent Developments
12.5 Aspen API
12.5.1 Aspen API Company Information, Head Office, Market Area, and Industry Position
12.5.2 Aspen API Estrogen API Models, Specifications, and Application
12.5.3 Aspen API Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.5.4 Aspen API Company Profile and Main Business
12.5.5 Aspen API Recent Developments
12.6 Gedeon Richter
12.6.1 Gedeon Richter Company Information, Head Office, Market Area, and Industry Position
12.6.2 Gedeon Richter Estrogen API Models, Specifications, and Application
12.6.3 Gedeon Richter Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.6.4 Gedeon Richter Company Profile and Main Business
12.6.5 Gedeon Richter Recent Developments
12.7 Zhejiang Xianju Pharmaceutical
12.7.1 Zhejiang Xianju Pharmaceutical Company Information, Head Office, Market Area, and Industry Position
12.7.2 Zhejiang Xianju Pharmaceutical Estrogen API Models, Specifications, and Application
12.7.3 Zhejiang Xianju Pharmaceutical Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.7.4 Zhejiang Xianju Pharmaceutical Company Profile and Main Business
12.7.5 Zhejiang Xianju Pharmaceutical Recent Developments
12.8 Humanwell Healthcare
12.8.1 Humanwell Healthcare Company Information, Head Office, Market Area, and Industry Position
12.8.2 Humanwell Healthcare Estrogen API Models, Specifications, and Application
12.8.3 Humanwell Healthcare Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.8.4 Humanwell Healthcare Company Profile and Main Business
12.8.5 Humanwell Healthcare Recent Developments
12.9 China Resources Zizhu Pharmaceutical
12.9.1 China Resources Zizhu Pharmaceutical Company Information, Head Office, Market Area, and Industry Position
12.9.2 China Resources Zizhu Pharmaceutical Estrogen API Models, Specifications, and Application
12.9.3 China Resources Zizhu Pharmaceutical Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.9.4 China Resources Zizhu Pharmaceutical Company Profile and Main Business
12.9.5 China Resources Zizhu Pharmaceutical Recent Developments
12.10 Hunan Kyf Pharmaceutical
12.10.1 Hunan Kyf Pharmaceutical Company Information, Head Office, Market Area, and Industry Position
12.10.2 Hunan Kyf Pharmaceutical Estrogen API Models, Specifications, and Application
12.10.3 Hunan Kyf Pharmaceutical Estrogen API Sales Volume, Revenue, Price and Gross Margin, 2020-2025
12.10.4 Hunan Kyf Pharmaceutical Company Profile and Main Business
12.10.5 Hunan Kyf Pharmaceutical Recent Developments

13 Conclusion

14 Appendix
14.1 Research Methodology
14.2 Data Source
14.2.1 Secondary Sources
14.2.2 Primary Sources
14.3 Market Estimation Model
14.4 Disclaimer

According to YH Research, the global market for Estrogen API should grow from US$ 117 million in 2024 to US$ 169 million by 2031, with a CAGR of 5.3% for the period of 2025-2031.

The strategic recalibration of 2025 U.S. tariff mechanisms is redefining global economic governance norms. This study deciphers the transmission mechanisms of tariff escalation pathways and global policy responses on corporate investment strategies, regional trade networks, and critical material supply architectures.

Estrogen API

According to YH Research, the global market for Estrogen API should grow from US$ 117 million in 2024 to US$ 169 million by 2031, with a CAGR of 5.3% for the period of 2025-2031.

Unit: US$ M

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In-depth insight into market trends

Estrogen API refers to the active pharmaceutical ingredients used to manufacture estrogen-based medications. It includes natural or synthetic estrogen compounds such as estradiol, estrogen derivatives, and their esters. Estrogen APIs are used to regulate female endocrine function, maintain secondary sexual characteristics, relieve menopausal symptoms, and help prevent osteoporosis. They are formulated into tablets, injections, gels, and transdermal patches for hormone replacement therapy, contraceptives, and certain cancer treatments. Manufacturing requires strict compliance with pharmacopoeial standards, including purity, impurity control, stability, and safety, to ensure therapeutic efficacy and reliability in clinical use.

In 2024, global sales of estrogen API reached 132.54 tons, with an average selling price of US$829/kg. Production capacity was approximately 400 tons, and the industry's gross profit margin was approximately 30%-40%. Cost structure: direct materials accounted for approximately 62%, manufacturing costs approximately 27%, and labor costs approximately 11%. Industry chain: upstream consists of starting materials and intermediates (chemical reagents, solvents, catalysts), while downstream comprises pharmaceutical manufacturers and the medical/end-user market.

Estrogen APIs occupy a strategic niche in women’s health, characterized by elevated technical and regulatory thresholds. The market is moving away from commoditized supply toward a premium on high-purity, well-characterized APIs that meet stringent pharmacopeial and regulator expectations. Technical differentiation — including particle engineering, controlled polymorphism, and reproducible micronization — builds clear value for formulation partners and can command premium positioning. Growth opportunities are tied to refined therapeutic regimens in women’s health, rising demand for reliable pharmaceutical-grade supply, and the expansion of CDMO services that specialize in hormonally active substances. Challenges are structural: intense regulatory scrutiny, environmental and occupational safety obligations for steroid chemistry, and the unpredictability of demand for niche, high-value orders which can complicate capacity planning. Success in this segment therefore depends on robust quality systems, validated processes, and close alignment with downstream formulators and regulators.

This report aims to provide a comprehensive study of the global market for Estrogen API.
Report Highlights:
(1) Global Estrogen API market size (sales volume & revenue), history data from 2020-2025, and forecast data from 2026 to 2031.

(2) Global Estrogen API market competitive situation, sales, revenue, price, and market share, from 2020 to 2025.

(3) China Estrogen API market competitive situation, sales, revenue, price, and market share, from 2020 to 2025.

(4) Global Estrogen API segment by region (or country), key regions cover the United States, Europe, China, Japan, South Korea, Southeast Asia, and India, etc.

(5) Global Estrogen API segment by Type, and by Application, and regional segment by Type, and by Application.

(6) Global major production regions of Estrogen API, capacity, production and trends.

(7) Estrogen API industry supply chain, upstream, midstream, and downstream analysis.

Market segment by regions, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, UK, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Australia, and Rest of Asia-Pacific)
South America (Brazil, Rest of South America)
Middle East & Africa
Market segment by Type, covers
Estradiol Series
Estriol Series
Estrone Series

Market segment by Hormone Type, covers
Estradiol
Ethinylestradiol
Estriol
Estrone
Other

Market segment by Source, covers
Natural Hormones
Synthetic Hormones

Market segment by Application, can be divided into
Oral Preparation
Topical Preparations

Market segment by players, this report covers
EUROAPI
Symbiotec
Valdepharm (Fareva)
Gonane Pharma
Aspen API
Gedeon Richter
Zhejiang Xianju Pharmaceutical
Humanwell Healthcare
China Resources Zizhu Pharmaceutical
Hunan Kyf Pharmaceutical