Mammalian Cell Line Development - Global and China Top Players Market Share and Ranking 2025- YH Research

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Mammalian Cell Line Development - Global and China Top Players Market Share and Ranking 2025

Publication Date: 2025-07-09
Report Id: 2119692
Industry: Medical Devices & Consumables
Report Page: 130
Chart: 129

PDF Download

Publication Date: 2025-07-09
Report Id: 2119692
Industry: Medical Devices & Consumables
Report Page: 130
Chart: 129

PDF Download

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Table of Contents
Description
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1 Market Overview
1.1 Mammalian Cell Line Development Definition
1.2 Global Mammalian Cell Line Development Market Size and Forecast
1.3 China Mammalian Cell Line Development Market Size and Forecast
1.4 Share of China Mammalian Cell Line Development Market with Respect to the Global Market
1.5 Mammalian Cell Line Development Market Size: China VS Global Growth Rate, 2020-2031
1.6 Mammalian Cell Line Development Market Dynamics
1.6.1 Mammalian Cell Line Development Market Drivers
1.6.2 Mammalian Cell Line Development Market Restraints
1.6.3 Mammalian Cell Line Development Industry Trends
1.6.4 Mammalian Cell Line Development Industry Policy

2 Global Leading Players and Market Share
2.1 By Revenue of Mammalian Cell Line Development, Global Market Share by Company, 2020-2025
2.2 Global Mammalian Cell Line Development Participants, Market Position (Tier 1, Tier 2, and Tier 3)
2.3 Global Mammalian Cell Line Development Concentration Ratio
2.4 Global Mammalian Cell Line Development Mergers & Acquisitions, Expansion Plans
2.5 Global Mammalian Cell Line Development Major Companies Product Type
2.6 Head Office and Area Served of Key Players

3 China Leading Players, Market Share and Ranking
3.1 By Revenue of Mammalian Cell Line Development, China Market Share by Company, 2020-2025
3.2 China Mammalian Cell Line Development Mammalian Cell Line Development Participants, Market Position (Tier 1, Tier 2, and Tier 3)

4 Industry Chain Analysis
4.1 Mammalian Cell Line Development Industry Chain
4.2 Mammalian Cell Line Development Upstream Analysis
4.2.1 Mammalian Cell Line Development Core Raw Materials
4.2.2 Main Manufacturers of Mammalian Cell Line Development Core Raw Materials
4.3 Midstream Analysis
4.4 Downstream Analysis
4.5 Mammalian Cell Line Development Production Mode
4.6 Mammalian Cell Line Development Procurement Model
4.7 Mammalian Cell Line Development Industry Sales Model and Sales Channels
4.7.1 Mammalian Cell Line Development Sales Model
4.7.2 Mammalian Cell Line Development Typical Distributors

5 Sights by Type
5.1 Mammalian Cell Line Development Classification
5.1.1 CHO (Chinese Hamster Ovary) Cells
5.1.2 HEK (Human Embryonic Kidney) Cells
5.1.3 NS0 (Mouse Myeloma) Cells
5.1.4 BHK (Baby Hamster Kidney) Cells
5.1.5 Others
5.2 by Type, Global Mammalian Cell Line Development Consumption Value & CAGR, 2020 VS 2024 VS 2031
5.3 by Type, Global Mammalian Cell Line Development Consumption Value, 2020-2031

6 Sights by Application
6.1 Mammalian Cell Line Development Segment by Application
6.1.1 Biopharmaceutical Production
6.1.2 Drug Discovery and Development
6.1.3 Toxicity Testing
6.1.4 Others
6.2 by Application, Global Mammalian Cell Line Development Consumption Value & CAGR, 2020 VS 2024 VS 2031
6.3 by Application, Global Mammalian Cell Line Development Consumption Value, 2020-2031

7 Sales Sights by Region
7.1 By Region, Global Mammalian Cell Line Development Consumption Value, 2020 VS 2024 VS 2031
7.2 By Region, Global Mammalian Cell Line Development Consumption Value, 2020-2031
7.3 North America
7.3.1 North America Mammalian Cell Line Development Market Size & Forecasts, 2020-2031
7.3.2 By Country, North America Mammalian Cell Line Development Market Size Market Share
7.4 Europe
7.4.1 Europe Mammalian Cell Line Development Market Size & Forecasts, 2020-2031
7.4.2 By Country, Europe Mammalian Cell Line Development Market Size Market Share
7.5 Asia Pacific
7.5.1 Asia Pacific Mammalian Cell Line Development Market Size & Forecasts, 2020-2031
7.5.2 By Country/Region, Asia Pacific Mammalian Cell Line Development Market Size Market Share
7.6 South America
7.6.1 South AmericaMammalian Cell Line Development Market Size & Forecasts, 2020-2031
7.6.2 By Country, South America Mammalian Cell Line Development Market Size Market Share
7.7 Middle East & Africa

8 Sales Sights by Country Level
8.1 By Country, Global Mammalian Cell Line Development Market Size & CAGR, 2020 VS 2024 VS 2031
8.2 By Country, Global Mammalian Cell Line Development Consumption Value, 2020-2031
8.3 United States
8.3.1 United States Mammalian Cell Line Development Market Size, 2020-2031
8.3.2 by Type, United States Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.3.3 by Application, United States Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.4 Europe
8.4.1 Europe Mammalian Cell Line Development Market Size, 2020-2031
8.4.2 by Type, Europe Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.4.3 by Application, Europe Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.5 China
8.5.1 China Mammalian Cell Line Development Market Size, 2020-2031
8.5.2 by Type, China Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.5.3 by Application, China Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.6 Japan
8.6.1 Japan Mammalian Cell Line Development Market Size, 2020-2031
8.6.2 by Type, Japan Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.6.3 by Application, Japan Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.7 South Korea
8.7.1 South Korea Mammalian Cell Line Development Market Size, 2020-2031
8.7.2 by Type, South Korea Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.7.3 by Application, South Korea Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.8 Southeast Asia
8.8.1 Southeast Asia Mammalian Cell Line Development Market Size, 2020-2031
8.8.2 by Type, Southeast Asia Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.8.3 by Application, Southeast Asia Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.9 India
8.9.1 India Mammalian Cell Line Development Market Size, 2020-2031
8.9.2 by Type, India Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.9.3 by Application, India Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.10 Middle East & Africa
8.10.1 Middle East & Africa Mammalian Cell Line Development Market Size, 2020-2031
8.10.2 by Type, Middle East & Africa Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031
8.10.3 by Application, Middle East & Africa Mammalian Cell Line Development Consumption Value Market Share, 2024 VS 2031

9 Company Profile
9.1 Thermo Fisher Scientific
9.1.1 Thermo Fisher Scientific Company Information, Head Office, Market Area, and Industry Position
9.1.2 Thermo Fisher Scientific Company Profile and Main Business
9.1.3 Thermo Fisher Scientific Mammalian Cell Line Development Models, Specifications, and Application
9.1.4 Thermo Fisher Scientific Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.1.5 Thermo Fisher Scientific Recent Developments
9.2 AGC Biologics
9.2.1 AGC Biologics Company Information, Head Office, Market Area, and Industry Position
9.2.2 AGC Biologics Company Profile and Main Business
9.2.3 AGC Biologics Mammalian Cell Line Development Models, Specifications, and Application
9.2.4 AGC Biologics Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.2.5 AGC Biologics Recent Developments
9.3 FyoniBio
9.3.1 FyoniBio Company Information, Head Office, Market Area, and Industry Position
9.3.2 FyoniBio Company Profile and Main Business
9.3.3 FyoniBio Mammalian Cell Line Development Models, Specifications, and Application
9.3.4 FyoniBio Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.3.5 FyoniBio Recent Developments
9.4 KBI Biopharma
9.4.1 KBI Biopharma Company Information, Head Office, Market Area, and Industry Position
9.4.2 KBI Biopharma Company Profile and Main Business
9.4.3 KBI Biopharma Mammalian Cell Line Development Models, Specifications, and Application
9.4.4 KBI Biopharma Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.4.5 KBI Biopharma Recent Developments
9.5 Hera Biolabs
9.5.1 Hera Biolabs Company Information, Head Office, Market Area, and Industry Position
9.5.2 Hera Biolabs Company Profile and Main Business
9.5.3 Hera Biolabs Mammalian Cell Line Development Models, Specifications, and Application
9.5.4 Hera Biolabs Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.5.5 Hera Biolabs Recent Developments
9.6 Catalent
9.6.1 Catalent Company Information, Head Office, Market Area, and Industry Position
9.6.2 Catalent Company Profile and Main Business
9.6.3 Catalent Mammalian Cell Line Development Models, Specifications, and Application
9.6.4 Catalent Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.6.5 Catalent Recent Developments
9.7 Bionova
9.7.1 Bionova Company Information, Head Office, Market Area, and Industry Position
9.7.2 Bionova Company Profile and Main Business
9.7.3 Bionova Mammalian Cell Line Development Models, Specifications, and Application
9.7.4 Bionova Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.7.5 Bionova Recent Developments
9.8 Lonza
9.8.1 Lonza Company Information, Head Office, Market Area, and Industry Position
9.8.2 Lonza Company Profile and Main Business
9.8.3 Lonza Mammalian Cell Line Development Models, Specifications, and Application
9.8.4 Lonza Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.8.5 Lonza Recent Developments
9.9 Creative Biolabs
9.9.1 Creative Biolabs Company Information, Head Office, Market Area, and Industry Position
9.9.2 Creative Biolabs Company Profile and Main Business
9.9.3 Creative Biolabs Mammalian Cell Line Development Models, Specifications, and Application
9.9.4 Creative Biolabs Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.9.5 Creative Biolabs Recent Developments
9.10 Fraunhofer
9.10.1 Fraunhofer Company Information, Head Office, Market Area, and Industry Position
9.10.2 Fraunhofer Company Profile and Main Business
9.10.3 Fraunhofer Mammalian Cell Line Development Models, Specifications, and Application
9.10.4 Fraunhofer Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.10.5 Fraunhofer Recent Developments
9.11 Cytena
9.11.1 Cytena Company Information, Head Office, Market Area, and Industry Position
9.11.2 Cytena Company Profile and Main Business
9.11.3 Cytena Mammalian Cell Line Development Models, Specifications, and Application
9.11.4 Cytena Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.11.5 Cytena Recent Developments
9.12 GTP Bioways
9.12.1 GTP Bioways Company Information, Head Office, Market Area, and Industry Position
9.12.2 GTP Bioways Company Profile and Main Business
9.12.3 GTP Bioways Mammalian Cell Line Development Models, Specifications, and Application
9.12.4 GTP Bioways Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.12.5 GTP Bioways Recent Developments
9.13 Abzena
9.13.1 Abzena Company Information, Head Office, Market Area, and Industry Position
9.13.2 Abzena Company Profile and Main Business
9.13.3 Abzena Mammalian Cell Line Development Models, Specifications, and Application
9.13.4 Abzena Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.13.5 Abzena Recent Developments
9.14 FUJIFILM Diosynth Biotechnologies
9.14.1 FUJIFILM Diosynth Biotechnologies Company Information, Head Office, Market Area, and Industry Position
9.14.2 FUJIFILM Diosynth Biotechnologies Company Profile and Main Business
9.14.3 FUJIFILM Diosynth Biotechnologies Mammalian Cell Line Development Models, Specifications, and Application
9.14.4 FUJIFILM Diosynth Biotechnologies Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.14.5 FUJIFILM Diosynth Biotechnologies Recent Developments
9.15 WuXi Biologics
9.15.1 WuXi Biologics Company Information, Head Office, Market Area, and Industry Position
9.15.2 WuXi Biologics Company Profile and Main Business
9.15.3 WuXi Biologics Mammalian Cell Line Development Models, Specifications, and Application
9.15.4 WuXi Biologics Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.15.5 WuXi Biologics Recent Developments
9.16 Northway Biotech
9.16.1 Northway Biotech Company Information, Head Office, Market Area, and Industry Position
9.16.2 Northway Biotech Company Profile and Main Business
9.16.3 Northway Biotech Mammalian Cell Line Development Models, Specifications, and Application
9.16.4 Northway Biotech Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.16.5 Northway Biotech Recent Developments
9.17 Sartorius
9.17.1 Sartorius Company Information, Head Office, Market Area, and Industry Position
9.17.2 Sartorius Company Profile and Main Business
9.17.3 Sartorius Mammalian Cell Line Development Models, Specifications, and Application
9.17.4 Sartorius Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.17.5 Sartorius Recent Developments
9.18 EirGenix
9.18.1 EirGenix Company Information, Head Office, Market Area, and Industry Position
9.18.2 EirGenix Company Profile and Main Business
9.18.3 EirGenix Mammalian Cell Line Development Models, Specifications, and Application
9.18.4 EirGenix Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.18.5 EirGenix Recent Developments
9.19 Tanvex
9.19.1 Tanvex Company Information, Head Office, Market Area, and Industry Position
9.19.2 Tanvex Company Profile and Main Business
9.19.3 Tanvex Mammalian Cell Line Development Models, Specifications, and Application
9.19.4 Tanvex Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.19.5 Tanvex Recent Developments
9.20 Menarini Biotech
9.20.1 Menarini Biotech Company Information, Head Office, Market Area, and Industry Position
9.20.2 Menarini Biotech Company Profile and Main Business
9.20.3 Menarini Biotech Mammalian Cell Line Development Models, Specifications, and Application
9.20.4 Menarini Biotech Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.20.5 Menarini Biotech Recent Developments
9.21 Creative Biogene
9.21.1 Creative Biogene Company Information, Head Office, Market Area, and Industry Position
9.21.2 Creative Biogene Company Profile and Main Business
9.21.3 Creative Biogene Mammalian Cell Line Development Models, Specifications, and Application
9.21.4 Creative Biogene Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.21.5 Creative Biogene Recent Developments
9.22 Rodon Biologics
9.22.1 Rodon Biologics Company Information, Head Office, Market Area, and Industry Position
9.22.2 Rodon Biologics Company Profile and Main Business
9.22.3 Rodon Biologics Mammalian Cell Line Development Models, Specifications, and Application
9.22.4 Rodon Biologics Mammalian Cell Line Development Revenue and Gross Margin, 2020-2025
9.22.5 Rodon Biologics Recent Developments

10 Conclusion

11 Appendix
11.1 Research Methodology
11.2 Data Source
11.2.1 Secondary Sources
11.2.2 Primary Sources
11.3 Market Estimation Model
11.4 Disclaimer

According to YH Research, the global market for Mammalian Cell Line Development should grow from US$ 272 million in 2024 to US$ 487 million by 2031, with a CAGR of 8.9% for the period of 2025-2031.

Mammalian cell line development refers to the process of creating and optimizing cell lines derived from mammalian species, such as humans, mice, or monkeys, for use in research, biopharmaceutical production, and other applications. This involves selecting a suitable cell type, establishing a stable cell line, and optimizing growth conditions to ensure high productivity and consistency. Mammalian cell lines are commonly used in the production of recombinant proteins, monoclonal antibodies, and vaccines, as they closely mimic the physiology and function of human cells, making them valuable tools for studying disease mechanisms and developing new therapies. The development of mammalian cell lines is a crucial step in biotechnology and biomedical research, enabling the production of complex biological molecules and advancing our understanding of human health and disease.

Mammalian Cell Line Development

According to YH Research, the global market for Mammalian Cell Line Development should grow from US$ 272 million in 2024 to US$ 487 million by 2031, with a CAGR of 8.9% for the period of 2025-2031.

Unit: US$ M

www.yhresearch.com

In-depth insight into market trends

The mammalian cell line development industry is undergoing transformative advancements driven by technological innovation, regulatory demands, and emerging therapeutic paradigms. A central trend is the accelerated adoption of CRISPR-Cas9 gene-editing technologies, which have revolutionized cell line optimization by enabling precise genomic modifications to enhance protein expression, metabolic pathways, and host cell resilience. Single-cell sequencing (scRNA-seq) and AI-driven analytics are reshaping cell line characterization and process optimization. By profiling thousands of individual cells, scRNA-seq identifies rare high-producing clones and uncovers heterogeneity in cell populations, while AI algorithms predict clone stability and optimize culture conditions. For example, AI models trained on multi-omics data can reduce clone screening time by 40% by prioritizing clones with favorable genetic and phenotypic profiles.
Continuous manufacturing and single-use technologies are also gaining traction, driven by the need for flexibility and cost efficiency. Single-use bioreactors and integrated downstream processing systems (e.g., chromatography columns) eliminate cleaning validation steps and reduce capital costs, while continuous perfusion cultures maintain high cell densities (>50 million cells/mL) and prolong production cycles, increasing volumetric productivity by 2–3 fold.
Regulatory pressures are pushing for enhanced quality control and traceability. The FDA’s 2023 establishment of the Office of Therapeutic Products (OTP) streamlines reviews for cell and gene therapies, emphasizing real-time monitoring and long-term safety data (e.g., 15-year follow-up for CAR-T patients). Meanwhile, emerging markets like China and India are driving growth, with China investing $58 million in stem cell research and India’s cell line development market projected to grow at 11.6% CAGR through 2030. These regions are leveraging cost-effective manufacturing and government incentives to become global hubs for biosimilars and novel biologics.
Challenges persist, including contamination risks (e.g., mycoplasma affecting 5–30% of cell cultures) and high development costs (e.g., a vial of CHO cells costs ~$4,250). However, advancements in automated imaging systems and CRISPR-based contamination detection tools are mitigating these issues.

This report studies and analyses global Mammalian Cell Line Development status and future trends, to help determine the Mammalian Cell Line Development market size of the total market opportunity by Type, by Application, by company, and by region & country. This report is a detailed and comprehensive analysis of the world market for Mammalian Cell Line Development, and provides market size (US$ million) and Year-over-Year growth, considering 2024 as the base year.

For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.

To assess the competitive environment within the market including supplier revenue, market share, and company profiles.

Highlights
(1) Global Mammalian Cell Line Development market size, history data 2020-2025, and forecast data 2026 -2031, (US$ million)
(2) Global Mammalian Cell Line Development by company, revenue, market share and industry ranking 2020-2025, (US$ million)
(3) China Mammalian Cell Line Development by company, revenue, market share and industry ranking 2020-2025, (US$ million)
(4) Global Mammalian Cell Line Development key consuming regions, consumption value and demand structure
(5) Mammalian Cell Line Development industry chains, upstream, midstream and downstream
Market segment by players, this report covers
Thermo Fisher Scientific
AGC Biologics
FyoniBio
KBI Biopharma
Hera Biolabs
Catalent
Bionova
Lonza
Creative Biolabs
Fraunhofer
Cytena
GTP Bioways
Abzena
FUJIFILM Diosynth Biotechnologies
WuXi Biologics
Northway Biotech
Sartorius
EirGenix
Tanvex
Menarini Biotech
Creative Biogene
Rodon Biologics

Market segment by Type, covers
CHO (Chinese Hamster Ovary) Cells
HEK (Human Embryonic Kidney) Cells
NS0 (Mouse Myeloma) Cells
BHK (Baby Hamster Kidney) Cells
Others

Market segment by Application, can be divided into
Biopharmaceutical Production
Drug Discovery and Development
Toxicity Testing
Others

Market segment by regions, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, UK, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Australia, and Rest of Asia-Pacific)
South America (Brazil, Rest of South America)
Middle East & Africa
Report Includes:
Chapter 1: to describe Mammalian Cell Line Development product scope, global consumption value, China consumption value, development opportunities, challenges, trends, and policies.
Chapter 2: Global Mammalian Cell Line Development market share and ranking of major manufacturers, revenue, 2020-2025
Chapter 3: China Mammalian Cell Line Development market share and ranking of major manufacturers, revenue, 2020-2025
Chapter 4: Mammalian Cell Line Development industry chain, upstream, medium-stream, and downstream.
Chapter 5: Segment by Type, consumption value, percent & CAGR, 2020-2031
Chapter 6: Segment by Application, consumption value, percent & CAGR, 2020-2031
Chapter 7: Segment in regional level, consumption value, percent & CAGR, 2020-2031
Chapter 8: Segment in country level, consumption value, percent & CAGR, 2020-2031
Chapter 9: Company profile, introducing the basic situation of the main companies in the market in detail, including product specifications, application, recent development, revenue, gross margin.
Chapter 10: Conclusions